Comparison of Scanned (fraxel repair) versus Randomized (Mosaic) fractional laser resurfacing 1550nm for the treatment of Asian patients

Takahiro Fujimoto, MD.,Ph.D.  Clinic F, Tokyo, Japan

EADV Spring 2009 in Romania

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Objective: There is a growing demand among patients and practitioners for a more aggressive treatment to address wrinkles and uneven texture while minimizing the recovery time experienced with other ablative technologies. The purpose of this clinical study was to determine the efficacy of fractional skin resurfacing utilizing scanned fractionated resurfacing laser

(Fraxel repair, Reliant, CA, USA) and randomized resurfacing laser (Mosaic, Lutronic, Seoul, South Korea) focusing on skin texture improvement and pore size reduction for Asian skin.

Subjects and Methods: Twenty-eight human subjects ranging in age from the mid-twenties to late fifties with skin types III to IV were treated at our clinic twice. Once by Fraxel and the other time by Mosaic. Wavelength of these two lasers are the same -1550nm, however, the way to approach their skin is different. Treatment sites were evaluated and compared with the baseline (pre-treatment) regarding the skin texture, pore size, fine wrinkles and spotty pigmentation.

Results: At 2 months’ follow-up, the investigators reported improvement in skin texture, pore size, fine wrinkles and spotty pigmentation compared with the baseline values. Patients’ satisfaction rate was deferent in each parameter respectively. There were no serious complications, including post inflammatory hyper-pigmentation.

Conclusions: Fractional Laser resurfacing treatment offers a safe, cosmetic method of improving skin texture, especially pore size reduction for Asian skin with no serious adverse sequelae.